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Frequency of adiponectin gene polymorphisms in polycystic ovary syndrome and the association with serum adiponectin, androgen levels, insulin resistance and clinical parameters
Demirci, Hueseyin; Yilmaz, Murat; Ergun, Mehmet Ali; Yurtcu, Erkan; Bukan, Neslihan; Ayvaz, Goeksun (Taylor & Francis Ltd, 2010)Materials and methods. Ninety-six patients with PCOS and 93 healthy control subjects were included in the study. Insulin resistance was estimated via HOMA-IR. Serum adiponectin levels were measured by ELISA. For determination ... -
Melanocortin-4 Receptor Gene Polymorphisms in Obese Patients
Yurtcu, Erkan; Yilmaz, Akin; Ozkurt, Zubeyde; Kolukisa, Emine; Yilmaz, Murat; Keles, Hatice; Menevse, Adnan (Springer/Plenum Publishers, 2009)Obesity is a complex disease caused by both genetics and environmental factors. Melanocortin-4 receptor (MC4R) (MIM 155541) gene polymorphisms were reported to be the cause of monogenic obesity in humans. We studied three ... -
Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene in women with polycystic ovary syndrome
Yilmaz, Murat; Erguen, Mehmet Ali; Karakoc, Ayhan; Yurtcu, Erkan; Cakir, Nuri; Arslan, Metin (Taylor & Francis Ltd, 2006)Aim. The present study was designed to examine the relationship between Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma gene (PPAR-gamma) and clinical and hormonal characteristics in women ...